Page 147 - 2015-16

CSIR-IHBT Annual Report 2015-16

glucopyranosyl-(1→4)]-α-L-arabino pyranosyl hederagenin 28-O-α-L-rhamnopyranosyl-
(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (1), on the basis of detailed analysis of
chemical and spectroscopic data including 1D- and 2D NMR. This is the first report for the
isolation of tomentoside A (2) from this genus and huzhangoside D (3) and clematoside S (4) from
this species. Compound 2 was found more effective against aphid, Aphis craccivora with an LC50
of 1.21 and 0.46 mg/L at 72 and 96 h after treatment respectively and was followed by compound 4
(LC50 = 2.33 and 1.88 mg/L) and 1 (LC50 = 3.17 and 2.60 mg/L). In case of termite (Coptotermis
homii), compound 1 was found more toxic with an LC50 of 0.12 mg/L after 24 h of treatment
followed by compound 2, 3 and 4 (LC50= 0.13, 0.15 and 0.19 mg/L respectively).

Publications:
· Kumar R, Kumar I, Sharma R and Sharma, U (2016). Catalyst and Solvent-Free alkylation
of Quinoline N-oxides with Olefins: Direct Access to Quinoline Substituted α–Hydroxy
Carboxylic Derivatives. Organic & Biomolecular Chemistry, 14: 2613-2617.
· Kumar D, Gulati A and Sharma U (2016) Determination of Theanine and Catechin in
Camellia sinesis (Kangra Tea) Leaves by HPTLC and NMR Technique. Food Analytical
Methods, 9(6): 1666-1674.
· Sharma R, Kumar R, Kumar I and Sharma U (2015) Rh(III)-Catalyzed Dehydrogenative
Coupling of Quinoline N-Oxides with Alkenes: N-Oxide as Traceless Directing Group for
Remote C-HActivation. European Journal of Organic Chemistry, 7519-7528.
· Sharma R, Thakur R, Kumar R, Kumar I and Sharma U (2015) Distant C-H
Activation/Functionalization: A New Horizon of Selectivity beyond Proximity. Catalysis
Reviews: Science and Engineering, 57(3): 345-405.
· Rattan R, Reddy SGE, Dolma SK, Fozdar BI, Gautam V, Sharma R and Sharma, U (2015)
Triterpenoid Saponins from Clematis graveolens and Evaluation of their Insecticidal
Activities. Natural Products Communications, 10(9): 1525-1528.

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